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Dyadic International, Inc. Q3 F2026 Earnings Call Transcript

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Operator
Conference Call Operator
Good evening and welcome to Dyadic International's Q3 2026 conference call.
Talith Korman
Analyst, Craig-Hallum Capital Group
Currently, all participants are in a listen-only mode.
Operator
Conference Call Operator
Following management's prepared remarks, there will be a brief question and answer session. As a reminder, this conference call is being recorded today, November 12, 2026. I would now like to turn the call over to Ms. Ping Rawson, Dyadic's Chief Financial Officer. Please go ahead.
Ping Rawson
Chief Financial Officer
Thank you. Good evening and welcome everyone to Dyadic's third quarter 2026 conference call. I hope you have had the opportunity to review Dyadic's press release announcing financial results for the quarter end of September 30, 2026. You may access our release under the investor session of the company's website at dyadic.com. Before we begin, I want to let you know that due to a Microsoft Outlook issue that has impacted many organizations, including Dyadic, we have not yet filed our quarterly report on Form 10-Q for the quarter ended September 30, 2026. We expect to file the Form 10-Q as soon as the system is back online and within the SEC filing deadline. The financial results we will discuss today are those in our press release and they will be reflected in the Form 10-Q. On today's call, our President and Chief Operating Officer, Joe Hazelton, will review our Q3 2026 business and corporate highlights and provide a commentary on the strategic direction of the company. Our CEO, Mark Emalfarb, will provide an update on our biopharmaceutical program. and I will follow with a review of our financial results in more detail, after which we will hold a brief question and answer session. At this time, I would like to inform you that certain commentary made in this conference call may be considered poor-looking statements, which involve risks and uncertainties and other factors that could cause bad actual results, performance, scientific or otherwise or achievements to be materially different from those expressed or implied by these forward-looking statements. DIATIC expressly disclaims any duty to provide updates to its forward-looking statements, whether because of new information, future events, or otherwise. Participants are directed to the risk factors set forth in DIATIC's reports filed with DASIC. It is now my pleasure to pass the call to our President and COO, and Joe Hazelton. Joe?
Joe Hazelton
President and Chief Operating Officer
Thanks, Ping, and thank you, everyone, for joining us today. Over the past several quarters, we've discussed ADDx's transition from primarily developing protein production technologies toward building commercial businesses around our C1 and Dappopus platforms. During the third quarter, we continued making progress in that transition through initial direct product sales, broader distribution, additional partner commercialized products, and advancing discussions with companies interested in our technologies and protein production portfolio. While these developments are encouraging, I want to put them in perspective. Our direct commercial sales remain modest and customer qualification and adoption are taking longer than we originally anticipated. While we still have work ahead of us to establish meaningful and recurring product revenue, however, we are beginning to demonstrate that our protein production platforms can support commercial products through multiple business models, including direct sales, distribution, licensing, and partner-led commercialization. And importantly, we believe our decades of commercial experience put us in a stronger position to pursue larger strategic opportunities. Now, let's walk through some of the developments during the quarter and explain how they connect to our broader strategy. Starting with life sciences, during the third quarter, Dyadic recorded its first direct commercial protein product sales, primarily involving recombinant transferin and DNase I. While these sales are not yet financially material, they further demonstrate the data can develop and commercialize recombinant enzymes and proteins, validating the potential of our proprietary fungal expression systems and complementing the products already being commercialized through our partners. Our immediate priority is to convert initial purchases and ongoing customer evaluations into repeat business. We continue to see increased sampling requests and customer evaluations, particularly for human and bovine transferrin across research, cell culture, and cultured meat applications. Transferrin remains an important commercial focus because of its role in cell culture media and the potential demand for consistent animal-free alternatives. As we've discussed previously, improvements in production yields and manufacturing economics are important to making these products competitive. But the qualification process takes time for higher value segments like cell culture media. Customers need to establish that a replacement protein performs consistently in their specific applications, meets their quality requirements, and can be supplied reliably at acceptable economics. We're supporting those evaluations and working to expand our customer base, but we recognize that the conversion from sampling to recurring purchases has been slower than anticipated. Alongside our direct sales efforts, we continue to expand our commercial reach through third party distribution. IBT Bioservices has now launched an initial portfolio of six dietic produced research use only recombinant protein products through its distribution network. This relationship provides access to an established customer base without requiring dietic to build substantial direct sales organization. We're also evaluating additional products for distribution and pursuing opportunities with other distributors and commercial partners. Our objective remains to build a capital-efficient commercial model that leverages established channels and partners. Another important part of our strategy is working with established companies that can take products developed using our platforms into their respective markets. ProLiant Health and Biologicals continues to expand its commercial activities around AlbuFreeDx, its recombinant human serum albumin produced using dyadic C1 platform. ProLiant has been presenting performance and analytical data supporting applications in diagnostic assays and protein stabilization and has outlined plans to introduce additional products targeting cell culture media and cell and gene therapy applications. These activities provide an opportunity to expand the number of commercial applications for animal-free albumin with potential future revenue participation for dyadic under our commercial arrangements. In food and nutrition, our partner Enzymes has now commercialized its second chymosin product using our dapabas platform. In November, Enzymes informed us that its first commercial sale of dapabas-produced camel chymosin occurred in October. As a result, we expect to receive a $225,000 contractual payment and recognize the associated revenue during the fourth quarter. This follows the earlier commercialization of bovine thymusin and further demonstrates the ability to develop and commercialize different products using the dapabis production system. What is particularly relevant about ProLiant Enzymes is that these are established commercial organizations bringing products produced with Dyadic's technologies to market. Although the revenue contribution to Dyadic remains at an early stage, These relationships provide evidence of commercial applicability that can be valuable when evaluating broader licensing, supply, and strategic partnership opportunities. Also in our food and nutrition business, alpha-lacta albumin remains one of our highest priority development and commercial opportunities. We continue to advance our collaboration with BrigBio to develop and scale Dapubis-produced bovine alpha-lacta albumin, an animal-free dairy protein with potential applications in nutritional products. Recently, we announced an expanded strategic collaboration with BrigBio and Strive Nutrition, bringing together complementary capabilities across the entire value chain. From Dyadic's Dapavis protein production platform and strain optimization expertise, to manufacturing scale-up, commercialization, and integration into finished consumer products. Importantly, this collaboration aligns protein development and manufacturing capabilities with Strive Nutrition, the intended end customer, which plans to integrate are precision fermented animal-free alpha-lactam albumin into its next-generation nutritional products. We believe this integrated approach provides a more direct pathway toward commercial-scale production, market adoption, and potential recurring revenue opportunities. Our technical focus remains on improving production yields, protein quality, and manufacturing economics to support competitive commercial-scale production. While we're encouraged by the progress, further optimization, application testing, regulatory work, and scale-up remain necessary before commercial production can be established. We're also continuing discussions with additional global companies regarding potential licensing, development, and commercial arrangements involving alpha-lacta albumin and other animal-free proteins in our portfolios. These discussions are particularly relevant because the larger food and nutrition markets require manufacturing capacity, capital investment, regulatory expertise, and established commercial distribution. Our strategy is to work with companies that already possess these capabilities rather than attempting to build the entire commercial infrastructure ourselves. Beyond bovine alpha-lacta albumin, we have developed production strains for human alpha-lacta albumin and human lactoferrin and are actively exploring licensing and strategic partnership opportunities for these products. We've also initiated development of recombinant bovine lactoferrin, further expanding our portfolio of animal-free nutritional proteins. In addition, we continue to advance other dairy proteins and enzymes through internal development programs and external collaborations, broadening the range of potential applications and commercial opportunities for our platforms. We believe this expanding portfolio combined with a growing interest from potential commercial partners positions Dyadic to pursue broader strategic relationships across the food nutrition market. In our bio-industrial segment, we continue to expand applications for our ADAPABIS platform across industrial enzymes and biomass processing. Our partner, Firmbox Bio, has launched Entryzyme, an ADAPABIS-produced enzyme product targeting biomass processing applications. We're also developing additional enzymes for use across biofuels, food and feed, and textile and paper processing markets. We are seeing increased interest in anthrazine and other industrial enzyme solutions, particularly in the biofuels and ethanol markets, where volatility in energy markets is contributing to renewed interest in alternative fuels and improved production economics. This has translated into a significant increase in sampling activity and discussions with potential customers and strategic partners. We believe our ability to develop customized enzyme solutions combined with the manufacturing efficiency and scalability of DAPBIS creates opportunities to address the evolving needs of these industries. As with our other commercial businesses, our focus is on working with partners that bring established manufacturing capabilities, industry expertise, and customer relationships to accelerate commercializations while limiting the capital Dyadic would otherwise need to invest independently. When we look across our businesses, we believe the progress we have made in commercializing products both directly and through our partners is strengthening the strategic value of our C1 and DAPAVIS platforms. We now have several examples of our technology supporting commercial products and generating revenue through different business models. ProLiant has commercialized recombinant human albumin using C1. Enzymes has commercialized two chymosin products using DAPAVIS. And Enthrezyme has entered the industrial market. These relationships demonstrate our ability to develop products that can be commercialized through established partners. More recently, our collaboration with Brigg Brio and Strive Nutrition brings together the key elements of the commercial value chain for Dapabis-produced alpha-lacta albumin, from strain development and manufacturing scale-up through to Strive, the intended end customer. This vertically integrated partnership provides a defined pathway toward potential commercial supply, subject to successful development, scale-up, and product qualifications. Together with our initial direct protein sales and expanding distribution network, we believe these developments provide meaningful progress and commercial validation of our platforms across life sciences, food and nutrition, and bio-industrial markets. While commercial revenues are modest, we believe this growing track record helps us reduce the technical and commercial uncertainties that prospective strategic partners must evaluate, placing Dyadic in a stronger position to pursue larger opportunities. This is increasingly where we intend to focus our efforts. Rather than independently funding the development and commercialization of every product, we believe greater value can be created by partnering with companies that have the capital, manufacturing infrastructure, and commercial capabilities to bring our technologies and products to market at scale. Accordingly, we're placing greater emphasis on larger strategic partnerships, licensing and supply arrangements, and other potential transactions involving our platforms, products, and commercial programs. We continue to evaluate all options to maximize the value of our platforms and assets, including financing alternatives, strategic partnerships, and other opportunities to strengthen our balance sheet, accelerate commercialization, and support long-term shareholder value. Our objective is to build on the commercial foundation we've established and translate that progress into larger opportunities that can deliver meaningful financial and strategic value for Dyadic and its shareholders. With that, I'll now turn the call over to Mark to discuss our biopharmaceutical programs and the continuing development of our C1 platform. Mark?
Mark Emalfarb
Chief Executive Officer
Thank you, Joe. The biopharmaceutical development, validation, and strategic operations and opportunities, as Joe discussed, are growing commercial activity to demonstrate the broad applicability of our C1 and DAPAVS protein production platforms in biopharmaceuticals We continue to build on this foundation by generating technical and preclinical data involving complex proteins, including monoclonal antibodies and vaccine antigens. Our biopharmaceutical strategy remains focused on externally funded development programs and strategic collaborations rather than independently financing costly clinical development programs. By working with established research institutions, Foundations, and industry partners, we aim to demonstrate C1's advantages in development, speed, productivity, protein quality, scalability, and manufacturing economics, while advancing its potential adoption by pharmaceutical and biotech companies. Let me highlight four important areas of progress. The first is the Gates Foundation program's advance to animal studies. Under our approximately $3.1 million Gates-funded program, C1 achieved productivity yields of approximately 12.1 grams per liter for RSV monoclonal antibody RSMO1 and 13.2 grams per liter for malaria monoclonal antibody MAMO1 in seven-day fermentations. Importantly, both C1-produced antibodies demonstrated approximately 90% human N-like glycan structures, supporting C1's ability to produce complex monoclonal antibodies with human-relevant glycosylation profiles. Independent evaluations by Duke University and IQVIA also demonstrated binding and neutralization activity comparable to their CHO-produced counterparts in the respective assays performed. Following the quarter end in October, 2026, the Gates Medical Research Institute initiated preclinical animal studies funded directly by the Gates Organization, comparing the pharmacokinetics of C1-produced RFV and malaria antibodies with the respective GMP-CHO-produced counterparts. Results are anticipated in the first quarter of 2027. These studies represent an important next step beyond laboratory testing towards potential clinical development. Together, the high production yields and Joseph Hazelton. We've completed a rapid vaccine antigen development project reducing timelines from months to approximately 15 days. Through the $4.5 million Coalition for Epidemic Preparedness Innovations, CEPI, funded program with Foundationi Biotechnology Siena, FBS, Dyadic developed a rapid C1 production workflow that reduced our previous development timeline from several months to approximately 15 days from plasmid to CTAG pure fiber common protein. We initially demonstrated this with our DY100 SARS-CoV-2 antigen. This progress was put to test during the Bundibugyo Ebola outbreak when we produced and purified two Scripps research design antigens in approximately 15 days and delivered them to FES for preclinical studies. These achievements build on encouraging results across multiple preclinical vaccine programs and our completed phase one DYA-100 clinical trial, which demonstrated safety, tolerability in both humoral and cellular immune responses. Together, they support C1's potential to accelerate vaccine development and improve responsiveness to emerging infectious disease threats. Third, we have further advanced our monoclonal antibody development and validation. Building on previously published research in Nature Communications demonstrating the protective efficacy of a C1-produced SARS-CoV-2 monoclonal antibody in non-human primates, we achieved another important milestone with Bundibugyo Ebola. We've demonstrated a rapid development process progressing from plasmid to a clonal production strain in protein A purified Bundibugyo Ebola monoclonal antibody in approximately seven weeks. Together with our Gates-funded RSV and malaria antibody results, these achievements provide further evidence of C1's ability to rapidly produce biologically functional monoclonal antibodies at high yield supporting its potential as an alternative to traditional mammalian cell manufacturing. Finally, we're continuing to advance through C1 third-party-funded collaborations involving CEPI, FBS, Scripps Research, the Gates Foundation, and the NIAID, NIH-supported researchers, and others. Through our collaboration with FBS, C1 is also being evaluated within the 170-million-euro Vaccines Hub Initiative. with funding awarded at the consortium level rather than directly to Dyadic. These relationships provide valuable opportunities to further evaluate C1 along leading vaccine and biological developers, strengthening its scientific and manufacturing validation, and support potential commercial adoption. As Joe noted, the commercial value of our protein production platforms does not depend on Dyadic independently developing clinical, advancing, or manufacturing every product. This is particularly important in biopharmaceuticals where clinical development and commercialization can require substantial capital and specialized infrastructure. Instead, our objective is to leverage the technical results and independent validation generated through these externally funded programs to pursue licensing arrangements, funded development programs, technology access agreements, and broader strategic relationships with pharmaceutical and biotechnology companies. We believe our demonstrated ability to rapidly produce complex vaccine antigens and monoclonal antibodies at high yields while maintaining biological functionality can make C1 an attractive option for organizations seeking faster, more scalable, and potentially lower cost alternatives to conventional manufacturing technologies. While additional validation and development remains necessary, The ongoing animal studies, rapid development milestones, and expanding collaborations continue to strengthen the technical foundation and potential strategic value of C1. Ultimately, our goal is to translate these capabilities into commercial partnerships that can accelerate the development and manufacture of biologic medicines, strengthen pandemic preparedness, reduce healthcare costs, and expand access to vaccines and therapeutics worldwide. Together with the commercial progress Joe outlined, we believe these developments position Dyadic to pursue additional opportunities to monetize our technology platforms, production capabilities, and manufacturing know-how. With that, I'll turn the call back to Ping for the financial review.
Ping Rawson
Chief Financial Officer
Thank you, Mark. I will now go over our key financial results for the third quarter of 2026 in more detail. You can find additional information in our earnings press release and form 10Q, which we expect to file as soon as the system is back online within the SEC filing deadline. Total revenue for the three months ended September 30, 2026 was approximately $449,000 compared to approximately $1,165,000 for the third quarter of 2025. The decrease of 61% was driven by a $538,000 decline in grant revenue, reflecting lower activity under the Gates Foundation and SAPI grants, and a $188,000 decline in research and development revenue as several collaboration projects were completed in the prior year period. Revenue for the quarter included approximately $162,000 of research and development revenue, $276,000 of grant revenue, and $10,000 of license fee revenue. For the first nine months of 2026, total revenue was 2.5 million, essentially flat compared to the same period in 2025. Total cost of revenue for the quarter was approximately $375,000, a decrease of 63% compared to approximately $1,024,000 for the last period, 2025. The decrease was primarily related to lower activity levels associated with our grant-funded programs. Internal research and development expenses decreased 25% year over year to approximately $430,000 compared to approximately $572,000 in the third quarter of 2025. The decrease reflects a $199,000 reduction in third-party contract research services as we continue to advance programs through externally funded collaborations and maintain disciplined internal R&D spending. For the nine months, internal research and development expenses were approximately $1.2 million, down 27% from approximately $1.7 million a year ago. G&A expenses decreased by $31,000 or 2% year-over-year to approximately $1.45 million compared to approximately $1.48 million in the third quarter of 2025. For the nine months, G&A expenses were approximately $4.9 million, an increase of 8.5% year-over-year. Lost from operations for the quarter was approximately $1.8 million compared to approximately $1.9 million in the prior year period. Total other income net was approximately $455,000, which includes a non-cash net gain of approximately $546,000 from the change in fair value of the warrant liability related to the warrants we issued in our August offering. Net of insurance cost allocated to those warrants. This gain is non-cash and will fluctuate with our share price in future quarters. Net loss for the quarter was approximately $1.4 million or $0.04 per share, compared to approximately $2 million or $0.06 per share for the third quarter of 2025. For the nine months That loss was approximately $5.4 million, or $0.15 per share, compared to $5.8 million, or $0.18 per share, for the first nine months of 2025. Turning to our balance sheet and cash, we ended the third quarter with approximately $6 million in cash, cash equivalents, restrict cash, and investment-grade securities, including accrued interest. compared to approximately 8.6 million at year end. During the quarter, we completed a registered direct offering with our concurrent private placements of warrants, which generated gross proceeds of 2.9 million. On cash usage, net cash used in operating activities was approximately 5.3 million for the first nine months, or approximately $590,000 per month, This figure includes costs of the Gates-funded program, which are paid from restricted cash. We expect our cash usage to continue at a similar level, although it will vary from quarter to quarter depending on the timing of research and development activities, grant funding, and commercial activities. As we mentioned on the call, we have been actively evaluating financing, alternatives, and other opportunities to strengthen our balance sheets. At the same time, we remain focused on disciplining the cash management, expanding commercial revenues, and leveraging third-party funding and strategic collaborations to support development activities. As Joe discussed, we recorded our first direct commercial product sales in the third quarter, and our partners continued to expand the commercialization of products built on our platforms. In addition, following quarter ends, Enzymes confirmed their first commercial scale of our second capital product. While these activities are still at an early stage, our objective remains to build recurring products and partnership revenues while carefully managing our operating expenses and capital requirements. With that, I will now ask the operator to begin our Q&A session. Each caller will be allowed one question and one follow-up question to provide all callers with an opportunity to participate. If time permits, the operator will allow additional questions from those who have already spoken. I will now ask the operator to begin our Q&A session, after which Joe Hazelton will provide closing remarks. Operator?
Operator
Conference Call Operator
Thank you. And if you would like to ask a question, press star 1 on your telephone keypad. A confirmation tone will indicate that your line is in the question queue. You may press star 2 if you would like to remove your question from the queue. For participants using speaker equipment, it may be necessary to pick up your handset before pressing the star keys. And once again, please limit yourself to one question and one follow-up question. One moment, please, while we poll for questions. Your first question comes from John Vandermosten. I'm sorry. I'm sorry. Your first question comes from Talith Korman with Craig Hallam Capital Group. Please state your question.
Talith Korman
Analyst, Craig-Hallum Capital Group
Hello, and thank you for taking the questions. This is Talith Korman on for Matt Hewitt. So circling back to your opening remarks, could you please describe why adoption is progressing slower than initially expected? Thank you.
Joe Hazelton
President and Chief Operating Officer
I can take that one. So the adoption is a little bit slower because they're incorporating into their workflows. So when you're doing cell culture media, let's just say for mammalian cell lines, when you substitute a product like transferrin or even an albumin, you need to ensure that that works in process before you would transition into your commercial cell line. So that is taking a little bit longer because there's a little more regulatory hurdles for them to overcome. The research products, though, are picking up because those don't require the same level of regulatory oversight or regulatory scrutiny that some of the products that are used to make human therapeutics are. So while these are not human therapeutic products, they're not actually going into a human being, when you're using it for cell culture media or cell and gene therapy, they're actually being used to produce a human therapeutic. So they do need to evaluate those products to ensure that they meet the quality metrics and perform exactly like the transfer they're using today so they don't end up obviously with issues. So that's what's causing the slow, or at least taking a little bit longer time than we had anticipated for them to complete these and obviously incorporate them into workflows.
Talith Korman
Analyst, Craig-Hallum Capital Group
Awesome, great. And then could you speak to anything about like Necessarily just commentary from customers working with your platforms, how they believe it could progress and their initial thoughts with that. Thank you.
Joe Hazelton
President and Chief Operating Officer
I think in cell culture, the actual feedback is very good. So far, the products have been working in cell culture applications. We've received good feedback and even data from some of the customers demonstrating in certain models. whether it's cultured meat or whether it is mammalian cell lines or even het cell lines that our transferrin is working. So the feedback has been good that our products are performing as they should, which is obviously what we hope. And ProLiant has actually put out some very good data on the recombinant human albumin that they're producing using our technology that's actually performing better than serum-derived albumin that you get from human blood. So I think the feedback is good, and I think we're obviously moving in the right direction.
Operator
Conference Call Operator
Thank you. Reminders to the audience, to ask a question, press star 1 on your phone now.
Talith Korman
Analyst, Craig-Hallum Capital Group
To remove yourself from the queue, press star 2.
Operator
Conference Call Operator
Your next question comes from Dick Williams with Williams Resource Group. Please state your question.
Dick Williams
Williams Resource Group
Yes, hi, Joe, and hi, Mark. This is for you, Joe. In terms of the release that we just came out with a day or so ago, with the two entities in which you've got a partnership of sorts going, obviously, I don't know and I'm not sure what you can offer in terms of the sharing arrangements and the revenue that will come out of that partnership, but it looks like the Next Step, is one single product that you've mentioned. And that product at a level of around 200 metric tons a year, it looks like, is between a $10 to $16 million business by itself. So if you can give some more color in that area as to how that triumphant works. and how we can add additional products to that area that would increase the market opportunity higher than the $10 to $16 million range.
Joe Hazelton
President and Chief Operating Officer
It's a great question, Dick, and absolutely. I obviously can't give guidance on what the financials will look like on it. However, you're exactly right. This is one product and one end customer. is, I guess, different with this partnership than previous ones is Strive Nutrition is the end customer. They've got products in the U.S. market at places like Walmart, CVS. That's where you'll see their products, their free milk products. And we're essentially, we've now vertically integrated the partnership to include the end customer. And as all of these products, or at least in Strive's case, they're starting to move towards animal-free or obviously these higher value proteins for their nutritional products. There are things like lactoferrin or even human alpha-lactoalbumin, potentially casein someday. So as you think about alpha-lactoalbumin, and I also talked about lactoferrin, those are the follow-on products. And remember, Strive is one customer, and they're an absolutely wonderful partner. They're going to be testing some of the protein that we're currently producing in application to see how it performs in their products. and then obviously the goal is that they'll use it in their commercial products over time. So our goal obviously is to expand that to other potential commercial partners. So it wouldn't just be one order of 200 metric tons. That's just for Strive. That's just what they want to use. It could be another two, three, 400 metric tons to somebody else. So that's how those systems or those markets grow based on the number of customers you're able to achieve or able to attain over time, and then the number of products that they're putting into the different formulations. So depending on whether they're working on, let's say, early life or infant nutrition or healthy aging, those type of products, those all have different amounts of different proteins, whether it's alpha-lactoferrin, caseins, beta-lactoglobulin, it all depends on the products they're looking to make. And again, it differs between customer, but this is just one customer. and obviously a great partner to start the process off with.
Dick Williams
Williams Resource Group
Okay, thanks Joe. I have one question for Mark. Mark, in terms of the things that we've just finished, it seems like we've made a milestone in terms of the announcement and that the next step for the antibodies is proceeding. Give us some color on where that's going, the timeline to go next steps for the two areas of disease that you've now been involved with here.
Mark Emalfarb
Chief Executive Officer
Yeah, so thanks, Jack. First of all, the antibody program, you know, as I mentioned, there's three legs of the stool going on right now. One was in COVID, of course, we demonstrated beyond like a mice study reaction with the non-human primates. and it demonstrated safety, efficacy and everything else, performance equal to the existing system. We just didn't get the money from the European Union to get it into humans at that point. So with the Gates Foundation, the malaria antibody and the RSV antibodies, the beautiful thing there is, you know, the Gates have the deep pocket that if this continues to proceed as it is, we next step would hopefully be able to put it into then going from the mice studies to a non-human primate, and then also in the human beings. And it's really a major milestone because the yield that they're seeing, and if you would ask them, and of course they highlighted this, are astronomical compared to what they're getting out of the CHO cells in half the time. So the cost of goods is really critical to them to get into these lower middle income countries. But that same technology platform is gonna be used and applied in neurology, oncology and immunology in this half a trillion dollar market of monoclonal antibodies if we can crack the code, which means the right quality at the right price at the right cost. And it's a faster, quicker way of doing that. And that takes us to the CEPI program with Rino Rappioli, the European Vaccine Hub, and all the work going on there. But we've shortened the timeline dramatically to address pandemics. It's also shorter to develop and Joseph Hazelton. Thank you very much. This particular animal study was actually funded by Gates MRI, and we didn't have to use the money that we already have to do that. So we're very excited about all these opportunities. We took the Ebola antibody, which is something that we also did very rapidly with the European Vaccine Hub and Rino Rappioli. And hopefully sometime in the next few months, we'll start getting some data on that. So we've demonstrated the speed that the world needs to meet the needs of a demand of a pandemic without mRNA. We believe that our cost structures gives significant advantages. And I think moving the right direction, unfortunately, takes slower than anyone would like because we don't have the money just to push it on our own and we're relying on third parties to do it. And we've got the right third parties that have the expertise from a regulatory perspective, from the commercial perspective. It's all going well. So hopefully that helps out.
Operator
Conference Call Operator
Thank you. and your next question comes from John Vandermosten with Zax. Please state your question.
John Vandermosten
Analyst, Zacks
Great, thank you and good evening everyone. Let me start out with a question on product sales. They were modest in the third quarter, but I'm wondering is that a good baseline as we look forward to fourth quarter in 2027? You guys mentioned you had kindness in sales in November. How should we look at that and think about, you know, maybe building off a small base?
Joe Hazelton
President and Chief Operating Officer
It's building off a small base and one of the things we don't have a lot of capital to basically put a lot of inventory out into the market. That is one of the issues and one of the reasons that we're growing slowly. We haven't been able to fill channels to a significant level. We're making to demand right now. That's one of the reasons that this is growing. Thank you very much. were also, now that the products are out and now that we have commercialized products both with ProLiant as well as with Enzymes, we're approaching larger companies because now we've de-risked the platforms and we've de-risked the products. They're being used in research, they're being used in food applications, they're now being used in cell culture. So now we're also getting data back in from a lot of the evaluations that are being done and some of the companies that have already bought some. that data is going back into building a better basically product monograph for whether it's transferring or whether it's DNAS 1. And we're hoping that that will spur larger orders with larger customers. So that's one of the main things for us is focusing on customers that can take large-scale orders and large-scale supply agreements and can fund actual manufacturing. So it's going to be a little slow. but the good news is it's starting to sell. It's starting to move. We just need to try to accelerate with larger customers that will actually put so many in up front and that can fund some of the manufacturing that we need to do. Okay.
John Vandermosten
Analyst, Zacks
Thanks, Joe. And then, you know, as we look at the STRIVE agreement, how is that agreement structured? I know you've had a few different kinds of structures in terms of like royalty or profit share. What is that one?
Joe Hazelton
President and Chief Operating Officer
This one is a supply agreement. So that's essentially what to think of it as a supply agreement. Right now, were developing and optimizing the strain. As we produce some of the protein, it'll be tested by STRIVE. They're going to test it in application, make sure that it performs digestibility studies and the things that they'll want to do for their own products. And then once we meet the economic threshold and regulatory threshold, which is a self-affirmed graph, I think we had that in the press release, and once we meet the economic thresholds of the agreement we signed, then the purchases will follow. So the initial is for 10 tons and then up to 200 tons in the following year. So it should ramp very quickly depending on how fast we can get to the right optimized yield for the product, bringing the cost to where it needs to be for these applications. But hopefully that will happen quickly.
Operator
Conference Call Operator
Thank you.
Mark Emalfarb
Chief Executive Officer
And I think, Joe, maybe you can talk about, again, as you mentioned earlier, Strive is one of many customers and not one of the largest that we're in discussions with.
Joe Hazelton
President and Chief Operating Officer
They are an excellent customer. They do have, obviously, national distribution here in the U.S., but Mark's right. There are other customers that are looking for alpha-lacta albumin and definitely for different uses. Strive is essentially healthy nutrition, sports nutrition. They're looking at potentially getting into healthy aging and other segments. But there are companies looking at this for early life, infant nutrition, that again could be an interesting opportunity. But there are tons of companies in the non-animal dairy space.
Operator
Conference Call Operator
Thank you. And there are no further questions. I will now turn the call over to Dyadic's president and COO, Joe Hazelton.
Joe Hazelton
President and Chief Operating Officer
Thank you. And thank you, everyone, who joined us today. As we close, I want to reinforce the direction we are taking Dyadic. We continue to make progress commercializing our technologies, both through our own product sales and through our partners, who have successfully brought products developed using our platforms to market. These activities remain early, and we recognize that building meaningful recurring commercial revenue will take additional time and execution. However, we believe the combination of commercial experience, improving production capabilities, and externally validated technical performance provides a stronger foundation for the next stage of Datix development. Our focus is increasingly on how to translate those capabilities into larger commercial and strategic opportunities. We believe the greatest potential value of our platforms may be realized by working with companies that have the resources, manufacturing infrastructure, and market access to commercialize our products and technologies at scale. That includes licensing and supply relationships, broader strategic partnerships, and other potential transactions that can strengthen our financial position and accelerate the commercial development of our assets. We recognize the importance of moving with great urgency, prioritizing our resources, and pursuing opportunities that can deliver meaningful value for shareholders. Our objective is to build on the technical and commercial foundation we've established and identify the most effective path to realize its value. We appreciate the continued support of our shareholders and partners and employees and we look forward to updating you on our progress. Thank you, everyone.
Operator
Conference Call Operator
This conference has now concluded. Thank you for attending today's presentation. You may now disconnect your lines at this time.